How to order Barbiturates Online. Now , what is Barbiturates? Barbiturates are products use for the nonselective central nervous system depressants which are primarily used as sedative hypnotics and also anticonvulsants in sub-hypnotic doses. The barbiturates and their sodium salts are subject to control.
Barbiturates are substituted pyrimidine derivatives in which the basic structure common to these drugs is barbituric acid, a substance which has no central nervous system (CNS) activity. CNS activity is obtained by substituting alkyl, alkenyl, or aryl groups on the pyrimidine ring.
These drugs are sometimes used to help patients relax before surgery. Some may also be used to control seizures (convulsions). Barbiturates have been used to treat nervous and sleep problems.
Dosages of barbiturates must be individualised with full knowledge of their particular characteristics and recommended rate of administration. Factors of consideration are the patient’s age, weight, and condition. Parenteral routes should be used only when oral administration is impossible or impractical.
Intramuscular injection of the sodium salts of barbiturates should be made deeply into a large muscle, and a volume of 5 mL should not be exceeded at any one site because of possible tissue irritation. After IM injection of a hypnotic dose, the patient’s vital signs should be monitored.
Dosage should be reduced for patients with impaired renal function or hepatic disease.
For individuals who are allergic to barbiturate products will find themselves having trouble in breathing, swelling face, lips, tongue and throat. In cases like these the individual should contact emergency immediately.
Obvious side effects include
Barbiturates may be habit forming. Tolerance and psychological and physical dependence may occur with continuing use. Barbiturates should be administered with caution, if at all, to patients who are mentally depressed, have suicidal tendencies, or a history of drug abuse.
Elderly or debilitated patients may react to barbiturates with marked excitement, depression, and confusion. In some persons, barbiturates repeatedly produce excitement rather than depression.
In patients with hepatic damage, barbiturates should be administered with caution and initially in reduced doses. Barbiturates should not be administered to patients showing the premonitory signs of hepatic coma.
Parenteral solutions of barbiturates are highly alkaline. Therefore, extreme care should be taken to avoid perivascular extravasation or intra-arterial injection. Extravascular injection may cause local tissue damage with subsequent necrosis; consequences of intra-arterial injection may vary from transient pain to gangrene of the limb. Any complaint of pain in the limb warrants stopping the injection.
Alcohol should not be consumed while taking barbiturates. Concurrent use of the barbiturates with other CNS depressants (e.g., alcohol, narcotics, tranquillisers, and antihistamines) may result in additional CNS depressant effects.
Always remember to keep all barbiturate drugs and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.